ABSTRACT
Objective To study the therapeutic effects of Shuanglong Prescription (SP) for experimental myocardial infarction in rats. Methods Rat models of myocardial infarction were induced by ligation of coronary artery. Fourteen days after treatment, myocardial infarction area, biochemical parameters and myocardial capillary density were detected to observe the effect of SP.Results After 14- day treatment, SP could reduce the area of myocardial infarction, increase the ratio of 6- keto- PGF1? and TXB2 and the capillary density.Conclusion SP has certain therapeutic effect for myocardial infarction in rats.
ABSTRACT
Recently, hepatocyte transplantation has been documented to be effective in the treatment of numerous hepatic diseases, including acute and chronic liver failure, genetic liver diseases, cirrhosis, and so on. Before it is widely used in clinic, there are a lot of problems to solve, such as the lack of cell source, cell proliferation, and immunological rejection. This review focuses on recent progress in the study of hepatocyte transplantation with respect to the animal model, cell source, and the existing problems, at the same time addressing the prospect of traditional Chinese materia medica on hepatocyte transplantation.